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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GATA2 All Species: 35.15
Human Site: S462 Identified Species: 64.44
UniProt: P23769 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23769 NP_001139133.1 480 50500 S462 T P T P I H P S S S L S F G H
Chimpanzee Pan troglodytes XP_507651 444 47996 S427 P T P M H P P S S L S F G P H
Rhesus Macaque Macaca mulatta XP_001097801 480 50467 S462 T P T P I H P S S S L S F G H
Dog Lupus familis XP_541740 480 50435 S462 T P T P I H P S S S L S F G H
Cat Felis silvestris
Mouse Mus musculus O09100 480 50449 S462 T P T P I H P S S S L S F G H
Rat Rattus norvegicus Q924Y4 480 50445 S462 T P T P I H P S S S L S F G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506274 481 52429 S463 T P T P I H P S S S I S F G H
Chicken Gallus gallus P23824 466 50132 S448 T P T P I H P S S S I S F G H
Frog Xenopus laevis P23770 452 48922 S434 T P T P I H P S S S L S F G H
Zebra Danio Brachydanio rerio Q91428 438 47572 S421 P T P M H P S S S L P F A S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91623 486 50616 S461 F S T A G S L S G A V V P H S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28515 416 44804 C399 D Q L E Y K T C P P M M V D F
Sea Urchin Strong. purpuratus NP_999704 431 45512 P414 S H H H V P V P C S L S L S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.9 99.7 98.9 N.A. 97.9 97.5 N.A. 46.5 87.2 83.9 63.3 N.A. 36.4 N.A. 28.9 40.8
Protein Similarity: 100 72 99.7 99.5 N.A. 98.5 98.5 N.A. 54.4 91.2 87.5 71.6 N.A. 48.3 N.A. 41.4 53.5
P-Site Identity: 100 26.6 100 100 N.A. 100 100 N.A. 93.3 93.3 100 20 N.A. 13.3 N.A. 0 20
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 100 100 20 N.A. 26.6 N.A. 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 16 62 0 8 % F
% Gly: 0 0 0 0 8 0 0 0 8 0 0 0 8 62 0 % G
% His: 0 8 8 8 16 62 0 0 0 0 0 0 0 8 77 % H
% Ile: 0 0 0 0 62 0 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 8 0 0 16 54 0 8 0 0 % L
% Met: 0 0 0 16 0 0 0 0 0 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 62 16 62 0 24 70 8 8 8 8 0 8 8 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 8 8 85 77 70 8 70 0 16 16 % S
% Thr: 62 16 70 0 0 0 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 8 0 0 0 8 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _